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| Functions |
Description |
Input |
Output |
| Conversion |
From protein 3D structure to Protein Folding Shape Code (PFSC ),which provides complete conformation description, including secondary structure fragments as well as tertiary structure fragments |
PDB file |
Screen display ; Save as a file with RTF, XML or Words format |
| Alignment |
Compare a pair of protein conformations in PFSC and make an quantitative assessment |
A pair of PFSC or a pair of PDB files |
Screen display ; Save as a file with RTF, XML or Words format |
| Search |
Discover fragments with conformation homology from a specific protein fingerprint database |
A piece of PFSC or a fragment defined in PDB |
Screen display ; Save as a file with RTF, XML or Words format |
| Prediction |
From a protein AA sequence to generate a Protein Folding Variation Matrix (PFVM),which has complete aggregation for local folding variations and comprehensive information for protein conformations |
a AA sequence in single letter |
Screen display ; Save as a file with RTF, XML or Words format |
| Mutation |
Provide information how mutation causes conformation changes, which help protein / peptide design |
A pair of AA sequences with mutations |
Screen display ; Save as a file with RTF, XML or Words format |
| Differentiation |
Provide information how protein differentiation relates to conformation difference, which helps to understand the differentiation of same protein in different organisms |
A pair of AA sequences of same protein from different organisms |
Screen display ; Save as a file with RTF, XML or Words format |
